A vaccine against the disease leishmaniasis could save tens of thousands of lives every year. Now, scientists report that they have used snippets of DNA to spur mice to fight back against the parasites responsible for the illness, an approach they hope to soon begin testing in people.Leishmaniasis is caused by microscopic parasites of the genus Leishmania; some 20 different species can sicken humans. Leishmaniasis hits poor residents of tropical countries the hardest. The sandflies that spread the disease are silent and smaller than a mosquito. After a sandfly’s bite injects them into the body, Leishmania cells can attack the skin or mucous membranes, causing ulcers or disfiguring lesions. In an often lethal variety of the disease, they damage the liver, spleen, and bone marrow. Although the disease’s toll isn’t certain, estimates suggest there are about 1.3 million new cases and up to 40,000 deaths each year.Leishmania parasites are tricky foes, and so far no vaccine has received approval for use in humans. One challenge is that the parasites lay low inside our cells, out of reach of the antibodies triggered by most other vaccines. The key to eradicating these sheltered invaders, researchers suspect, is stimulating the immune cells known as T cells. Although two experimental leishmaniasis vaccines that use this strategy have undergone preliminary safety and effectiveness tests in people, the best method for enlisting T cells isn’t clear.Sign up for our daily newsletterGet more great content like this delivered right to you!Country *AfghanistanAland IslandsAlbaniaAlgeriaAndorraAngolaAnguillaAntarcticaAntigua and BarbudaArgentinaArmeniaArubaAustraliaAustriaAzerbaijanBahamasBahrainBangladeshBarbadosBelarusBelgiumBelizeBeninBermudaBhutanBolivia, Plurinational State ofBonaire, Sint Eustatius and SabaBosnia and HerzegovinaBotswanaBouvet IslandBrazilBritish Indian Ocean TerritoryBrunei DarussalamBulgariaBurkina FasoBurundiCambodiaCameroonCanadaCape VerdeCayman IslandsCentral African RepublicChadChileChinaChristmas IslandCocos (Keeling) IslandsColombiaComorosCongoCongo, The Democratic Republic of theCook IslandsCosta RicaCote D’IvoireCroatiaCubaCuraçaoCyprusCzech RepublicDenmarkDjiboutiDominicaDominican RepublicEcuadorEgyptEl SalvadorEquatorial GuineaEritreaEstoniaEthiopiaFalkland Islands (Malvinas)Faroe IslandsFijiFinlandFranceFrench GuianaFrench PolynesiaFrench Southern TerritoriesGabonGambiaGeorgiaGermanyGhanaGibraltarGreeceGreenlandGrenadaGuadeloupeGuatemalaGuernseyGuineaGuinea-BissauGuyanaHaitiHeard Island and Mcdonald IslandsHoly See (Vatican City State)HondurasHong KongHungaryIcelandIndiaIndonesiaIran, Islamic Republic ofIraqIrelandIsle of ManIsraelItalyJamaicaJapanJerseyJordanKazakhstanKenyaKiribatiKorea, Democratic People’s Republic ofKorea, Republic ofKuwaitKyrgyzstanLao People’s Democratic RepublicLatviaLebanonLesothoLiberiaLibyan Arab JamahiriyaLiechtensteinLithuaniaLuxembourgMacaoMacedonia, The Former Yugoslav Republic ofMadagascarMalawiMalaysiaMaldivesMaliMaltaMartiniqueMauritaniaMauritiusMayotteMexicoMoldova, Republic ofMonacoMongoliaMontenegroMontserratMoroccoMozambiqueMyanmarNamibiaNauruNepalNetherlandsNew CaledoniaNew ZealandNicaraguaNigerNigeriaNiueNorfolk IslandNorwayOmanPakistanPalestinianPanamaPapua New GuineaParaguayPeruPhilippinesPitcairnPolandPortugalQatarReunionRomaniaRussian FederationRWANDASaint Barthélemy Saint Helena, Ascension and Tristan da CunhaSaint Kitts and NevisSaint LuciaSaint Martin (French part)Saint Pierre and MiquelonSaint Vincent and the GrenadinesSamoaSan MarinoSao Tome and PrincipeSaudi ArabiaSenegalSerbiaSeychellesSierra LeoneSingaporeSint Maarten (Dutch part)SlovakiaSloveniaSolomon IslandsSomaliaSouth AfricaSouth Georgia and the South Sandwich IslandsSouth SudanSpainSri LankaSudanSurinameSvalbard and Jan MayenSwazilandSwedenSwitzerlandSyrian Arab RepublicTaiwanTajikistanTanzania, United Republic ofThailandTimor-LesteTogoTokelauTongaTrinidad and TobagoTunisiaTurkeyTurkmenistanTurks and Caicos IslandsTuvaluUgandaUkraineUnited Arab EmiratesUnited KingdomUnited StatesUruguayUzbekistanVanuatuVenezuela, Bolivarian Republic ofVietnamVirgin Islands, BritishWallis and FutunaWestern SaharaYemenZambiaZimbabweI also wish to receive emails from AAAS/Science and Science advertisers, including information on products, services and special offers which may include but are not limited to news, careers information & upcoming events.Required fields are included by an asterisk(*)Immunologist Peter Walden of Charité University Medicine Berlin and colleagues decided to try a DNA vaccine, a type of vaccine that is good at inciting T cells. Such vaccines contain DNA strands coding for proteins from a pathogen. Cells in the vaccine recipient’s body absorb the DNA and start churning out the proteins—also called antigens—which alert the immune system and prime it to attack if a real infection occurs.First, the researchers had to choose the right antigens. They settled on five different proteins that vary little across Leishmania samples from a range of species found around the world. To determine whether the antigens galvanize human T cells, the team obtained blood samples from people in India and Tunisia who had recovered from the disease or had been exposed to it without getting sick. They found that portions of all five proteins sparked a response by T cells from the blood samples.The researchers’ final vaccine mixture, which they tested in mice, contained five kinds of DNA strands, each coding for all or part of one of the proteins. The vaccine stimulated the mice to produce defenses against leishmaniasis parasites, Walden and colleagues report online today in Science Translational Medicine. T cells from the vaccinated animals reacted vigorously to Leishmania antigens. To confirm that the vaccine helped the animals combat the invaders, the researchers injected the mice with cells of one Leishmania species. Three weeks later, mice that received the highest vaccine dose carried 94% fewer parasites in their liver than did mice that received a control shot. Although some parasites remained in the mice that received the largest dose, Walden says there weren’t enough of them to cause disease symptoms.“We are ready for human trials,” he says. The vaccine should provide protection against different human Leishmania species, he adds, because the selected antigens are the same across species.Immunologist Paul Kaye of the University of York in the United Kingdom agrees that the time for human trials has come. “There is every reason to believe that they should move forward as soon as possible,” says Kaye, who’s excited that there are now three vaccines to try in humans. Kaye and colleagues’ own vaccine candidate, which stimulates T cells with a harmless virus that carries sections of two Leishmania genes, has already undergone a safety study in people, but the results have not yet been published.“This is a significant advance,” says vector biologist Jesus Valenzuela of the National Institute of Allergy and Infectious Diseases in Rockville, Maryland. Walden’s group deserves credit for using human blood samples to identify the antigens, he says; other vaccine developers have used rodents.Leishmaniasis is one of the neglected tropical diseases for which research cash is hard to obtain. Still, Walden is hopeful that he and his colleagues will find financing for safety trials.
The Board of Control for Cricket in India (BCCI) on Thursday made it clear that former India batsman V.V.S. Laxman was not involved in any conflict of interest at the time of selection of the head coach of the national cricket team.Reports emerged that Laxman, who is part of the Cricket Advisory Committee (CAC) comprising Sachin Tendulkar and Sourav Ganguly, which selected spin legend Anil Kumble as head coach, is a shareholder in Kumble’s company Tenvic Sports Education Private Ltd, for which the board had issued a clarification. (Also read: Murali Vijay excited as Anil Kumble joins forces with Team India) According to a statement from the board, Laxman had informed BCCI that he had sold his total shareholding of five per cent in Tenvic Sport in March and also declared that he no longer held any shareholding or any official or unofficial position in the company.”The BCCI would like to inform all concerned that at the time prior to the commencement of the functioning of the committee to interview applicants for the job of head coach of the Indian cricket team, V.V.S Laxman had very categorically clarified his current position as well his previous association with Tenvic Sports,” BCCI said in a release.”It was during the course of the requisite communication, Laxman informed BCCI that he had sold his total shareholding of five per cent in Tenvic Sport in the month of March and also declared that he no longer held any shareholding or any official or unofficial position in Tenvic Sports. This took place prior to the commencement of the operations of this committee.”advertisement”Laxman was, therefore, in no position of a conflict of interest at the time of selection of the head coach of Indian cricket team. All assumptions and conclusions to that effect are therefore erroneous,” the release added.
Priority legislation in the 18th Congress After losing in the finals in 2018, UP nearly got back in the championship round but lost twice to University of Santo Tomas in the Season 82 stepladder semifinals, leaving Perasol uncertain of his future with the team.“It really depends on the administration, and if you ask me I’d just want to rest and just watch games,” said Perasol in Filipino after the Fighting Maroons’ 68-65 loss to the Growling Tigers Wednesday at Mall of Asia Arena.FEATURED STORIESSPORTSGreatest ever?SPORTSFormer PBA import Anthony Grundy passes away at 40SPORTSSan Miguel suspends Santos, Nabong, Tubid indefinitely after ‘tussle’ in practice“I told them that whatever happens I hope that we should set a bar. We shouldn’t start from the bottom, we need to start from here, on top. The strength of our program shouldn’t be based on personality.”Perasol said that UP should have a basketball program that resembles Ateneo or De La Salle, two schools that have remained powers in the UAAP no matter who the coaches or players are. Coming into the season, UP was seen as one of the potential title-holders, boasting of a roster consisting of names any coach would want on his team.Season 81 MVP Bright Akhuetie was the anchor in the paint with Kobe Paras, a former NCAA Division I recruit and member of the national team program, Season 80 Rookie of the Year Juan Gomez de Liaño, and one-time UAAP champion Ricci Rivero in tow.The Fighting Maroons also had veteran Jun Manzo and valuable support players in Javi Gomez de Liaño and Janjan Jaboneta, but that collection of names failed to live up to the hype it produced.“On hindsight, what I want to see is all the things we’ve achieved in the past four years,” said Perasol, who played for the Fighting Maroons from the late 80s to early 90s. “They saw it and I hope they appreciate it because it’s time to move on.”It was a tough loss for UP, which had a four-point lead heading into the crucial stretch but gave the Growling Tigers enough space to snatch back the lead, 66-65, en route to the finals berth.ADVERTISEMENT Trending Articles PLAY LIST 00:50Trending Articles00:59Sports venues to be ready in time for SEA Games01:27Filipino athletes get grand send-off ahead of SEA Games02:11Makabayan bloc defends protesting workers, tells Año to ‘shut up’03:07PH billiards team upbeat about gold medal chances in SEA Games01:38‘Bato’ to be ‘most effective’ CHR head? It’s for public to decide – Gascon02:07Aquino to Filipinos: Stand up vs abuses before you suffer De Lima’s ordeal01:28Ex-President Noynoy Aquino admits contracting pneumonia00:45Aquino agrees with Drilon on SEA games ‘kaldero’ spending issue For the complete collegiate sports coverage including scores, schedules and stories, visit Inquirer Varsity. Ethel Booba on SEA Games cauldron: ‘Sulit kung corrupt ang panggatong’ Onyok Velasco see bright future for PH boxing in Olympics LATEST STORIES Matteo Guidicelli had saved up for Sarah G’s ring since 2014? What’s behind the display of Chinese flag in Boracay? Photo by Tristan Tamayo/INQUIRER.netMANILA, Philippines—Bo Perasol’s tenure as the head coach of University of the Philippines has been largely excellent.Perasol took over the Fighting Maroons in Season 79 and catapulted the team to the title picture just two seasons later when they challenged Ateneo for the Season 81 championship.ADVERTISEMENT Duterte calls himself, Go, Cayetano ‘the brightest stars’ in PH politics Don’t miss out on the latest news and information. MOST READ Sports Related Videospowered by AdSparcRead Next “I think what disappointed a lot in our community is by not being in the finals but we have to move forward on how we can bring this team back again to the championship round,” said Perasol. “We’re just one win away but we played against a very tough team.” Duterte officials’ paranoia is ‘singularly myopic’ Rice industry paralysis Drilon apologizes to BCDA’s Dizon over false claim on designer of P50-M ‘kaldero’ View comments
The LG G6, which is scheduled to launch in India on April 24, will start at Rs 51,990 and will go on sale from April 29, according to Mumbai-based retailer Mahesh Telecom. The G6 will further be available alongside a barrage – four to be precise – of offers including a Rs 7,000 cash back on HDFC and SBI credit and debit card on both EMI and non-EMI transactions, the retailer wrote on Twitter.Should the price and availability be close to what the retailer has mentioned – which going by his track record, it should – the LG G6 will have a competitive edge over Samsung’s Galaxy S8 and Galaxy S8+ phones. The Galaxy S8 starts at Rs 57,900 and will be available for buying from May 5.*Pre-Book the #LGG6 (?51990/-)*stock availability-29th April *Get 4 offers mentioned in the below image pic.twitter.com/wIKFNogd5S- Mahesh Telecom (@MAHESHTELECOM) April 21, 2017The LG G6, to recall, was first announced at the Mobile World Congress in Barcelona in February. Successor to last year’s modular phone, the G5, the LG G6 comes with an unusual 18:9 Full Vision display — instead of a regular 16:9 — and a wide-angle 13-megapixel dual rear camera system.On the inside, the phone is powered by a 2.35GHz quad-core Qualcomm Snapdragon 821 processor clubbed with Adreno 530 GPU and 4GB of RAM. It comes with 32/64GB of internal memory which is further expandable via a microSD card slot. It is further backed by a 3,300mAh battery with support for fast charging.The G6 comes with a dual camera system on the rear, consisting of two 13-megapixel sensors – – offering a 125-degree wide angle — with one working ‘specifically’ to offer the wider field of view. It also sports a 5-megapixel camera with a ‘wide’ 100-degree field of view on the front.advertisementAlso Read: LG G6 India launch set for April 24
LONDON — The New York Jets piled up the yards, both good and bad, and got the win they came for.The Jets (3-1) gained 425 yards of total offense, including a career-high 166 for running back Chris Ivory, in a 27-14 win over the Miami Dolphins on Oct. 4 at Wembley Stadium.But as much as the offensive yardage helped, it was the 163 yards given up on 14 penalties that kept the Dolphins (1-3) in the game. “We play aggressive, so some of that’s going to happen,” Jets linebacker Calvin Pace said. “But we know we’ve got to clean up our play.”Ryan Fitzpatrick started things for the Jets by completing a 58-yard pass to Brandon Marshall on the team’s first play from scrimmage. Ivory then ran for 12 yards and scored from the 3 on the next two plays as the offensive line neutralized Dolphins tackle Ndamukong Suh all day.Ivory kept getting the ball, and kept running effectively, carrying 29 times for an average of 5.7 yards per run. “When the back is going good, you keep feeding him,” Jets coach Todd Bowles said.Fitzpatrick ended up with 218 yards passing, one touchdown and one interception in the first division game played in London, and the first of three regular-season games to be played this year at Wembley.Suh, the highest-paid defensive player in league history, had only three tackles. His first didn’t come until the third quarter. “It wasn’t easy, man, that’s a good defense,” Jets right tackle Breno Giacomini said. “Suh, (Cameron) Wake, their whole defense, they gave us a good fight, and (it) felt good to get a win from them.”Both teams have byes next week, as usual for teams playing in London. But Miami, which has now lost three straight, will face lots of questions about its poor performances thus far.When they return to the field on Oct. 18, the Dolphins will play at Tennessee; the Jets will host the Washington Redskins.Dolphins coach Joe Philbin said he wasn’t worried about his job. “Not at all,” Philbin said. “I’m worried about getting our team fixed and straightened out and ready to play the Tennessee Titans. We have 14 days.”The hard-running Ivory scored the first touchdown from 3 yards to start off his ninth career 100-yard game. Fitzpatrick later completed a 10-yard TD pass to Eric Decker in the second quarter and Zac Stacy rushed in from the 2 in the third.Nick Folk converted all three extra points and added field goals from 22 and 48 yards. But he missed a 40-yard attempt.The Jets ended up with 207 yards rushing, including 34 from Fitzpatrick. Ivory’s 166 yards were the most by a Jet since Thomas Jones ran for 210 in 2009.Besides controlling Suh, the Jets got some help when Dolphins cornerback Brent Grimes went out with a right knee injury in the first quarter.The Jets gave the Dolphins some hope, though, with all those penalties. And Miami’s first score, in the second quarter, came with plenty of aid from New York’s secondary.Ryan Tannehill threw deep to Jarvis Landry, and Darrelle Revis was called for a 36-yard pass interference. On the next play, Tannehill threw to Jordan Cameron, but Marcus Gilchrist was whistled for another pass interference, good for 22 yards.Tannehill found Jake Stoneburner on the next play for 8 yards make the score 13-7.Tannehill ended up with 198 yards and two touchdowns on 19 of 44 passing. His second score was a 10-yard pass to Kenny Stills in the fourth quarter.But the Dolphins failed to come up with the big play, going 0 for 12 on third downs and 0 for 4 on fourth downs.“We’ve got to find a way to make plays. As ugly as it may have seemed, at the end of the day we had opportunities to win that game,” Philbin said. “We can’t panic. It can seem like the walls are closing in on you.”It was the 12th regular-season NFL game at Wembley Stadium, the home of England’s national soccer team. Later this season, Buffalo will take on Jacksonville on Oct. 25, and Detroit will face Kansas City on Nov. 1.It was the first time the Jets played in the NFL’s International Series, the third time for the Dolphins. They lost the first game in 2007, 13-10 to the New York Giants. Last year, the Dolphins beat the Oakland Raiders 38-14.(CHRIS LEHOURITES, AP Sports Writer) TweetPinShare0 Shares
FILE – In this June 7, 2018, file photo, New England Patriots owner Robert Kraft speaks with reporters following an NFL football minicamp practice, in Foxborough, Mass. Police in Florida have charged New England Patriots owner Robert Kraft with misdemeanor solicitation of prostitution, saying they have videotape of him paying for a sex act inside an illicit massage parlor. Jupiter police told reporters Friday, Feb. 22, 2019, that the 77-year-old Kraft has not been arrested. (AP Photo/Steven Senne, File)Kraft, who made his initial fortune through a packaging company, bought the Patriots in 1994 for $172 million to keep the team from moving to St. Louis. He hired Bill Belichick as coach in 2000, and the team later drafted quarterback Tom Brady, launching its nearly two decades of success.In 2007, the Patriots got in trouble for filming other teams’ signals. The NFL fined the team $250,000 and Belichick $500,000. In 2014, Brady was accused of delating game footballs to gain a better grip. He served a four-game suspension, and the Patriots were fined $1 million.Kraft was not implicated in either scandal.TweetPinShare0 Shares By Terry Spencer and Joshua Replogle, Associated PressJUPITER, Fla. (AP) — New England Patriots owner Robert Kraft faces misdemeanor charges of soliciting a prostitute after he was twice videotaped in a sex act at a Florida massage parlor, police said Friday in a case that could get him in trouble with the NFL.The 77-year-old Kraft denied any wrongdoing.He was not immediately arrested. Jupiter police said a warrant will be issued and his attorneys will be notified. They said details about the charges against the owner of the Super Bowl champion team will not be released until next week.The charge comes amid a crackdown on sex trafficking from Palm Beach to Orlando in which police planted cameras in massage parlors.Hundreds of arrest warrants have been issued in recent days as a result of a six-month investigation, and more are expected. Ten spas have been closed, and several people have been taken into custody on sex trafficking charges. A sign is posted outside of Orchids of Asia Day Spa, Friday, Feb. 19 ,2019, in Jupiter, Fla. Jupiter police have charged New England Patriots owner Robert Kraft with misdemeanor solicitation of prostitution. Jupiter Police Chief Daniel Kerr said Friday, that he was shocked to learn Kraft, who is worth $6 billion, was paying for sex inside a strip-mall massage parlor, the Orchids of Asia Day Spa. (/Palm Beach Post via AP)Jupiter police Chief Daniel Kerr said he was shocked to learn that Kraft, who is worth $6 billion, was paying for sex inside a shopping-center massage parlor, the Orchids of Asia Day Spa. “We are as equally stunned as everyone else,” Kerr said.Most people charged for the first time with soliciting a prostitute in Florida are allowed to enter a diversion program, said attorney David Weinstein, a former prosecutor. Kraft would probably have to perform 100 hours of community service and attend a course on the harmful effects of prostitution and sex trafficking, he said.The NFL did not immediately respond to a message seeking comment. Under league policy, players, owners, coaches and other employees can be punished for “conduct detrimental to the integrity of and public confidence in” the NFL.“Ownership and club or league management have traditionally been held to a higher standard and will be subject to more significant discipline,” the policy says.The Patriots won the Super Bowl this month over the Los Angeles Rams for their sixth NFL championship in the past 18 seasons, making them the most successful team in pro sports during that span.Kraft lives in Massachusetts and has a home in the Palm Beach area. Though he is a Democrat, he is friendly with President Donald Trump and a frequent guest at Trump’s Mar-a-Lago club. Kraft’s wife, Myra Hiatt Kraft, died in 2011. He has been dating 39-year-old actress Ricki Noel Lander since 2012.In a statement, Kraft’s representatives said they “categorically deny that Mr. Kraft engaged in any illegal activity.”Vero Beach police Chief David Currey, whose agency has been involved in the sex-trafficking investigation, told reporters earlier this week that the prostitutes are victims who have been trapped into the trade.“These girls are there all day long, into the evening. They can’t leave and they are performing sex acts,” Currey said, according to TCPalm. “Some of them may tell us they’re OK, but they’re not.”
A-League Sydney derby smashed in television ratings by WBBL Goal Last updated 1 year ago 06:42 12/12/17 FacebookTwitterRedditcopy Comments(0) A-League Western Sydney Wanderers v Sydney Sydney Western Sydney Wanderers The A-League’s showpiece regular season game has been put in its place by the women’s sport revolution The Sydney football derby has been heavily defeated by the Women’s Big Bash League (WBBL) in the TV ratings war as interest continues to decline in the A-League.A peak audience of 469,000 tuned in on Channel 10 to watch the WBBL cricket match between the Melbourne Stars and Sydney Sixers on Saturday night, while only 55,000 watched Sydney FC romp to a 5-0 victory over the Western Sydney Wanderers on ONE HD. Sat TV #ALeague #ONE #SydneyDerby 55k pic.twitter.com/fIxuNeSIJu— Mediaweek (@MediaweekAUS) December 9, 2017 The pay-TV figures for the derby weren’t much better with only 81,000 flicking on Fox Sports’ coverage. Article continues below Editors’ Picks Lyon treble & England heartbreak: The full story behind Lucy Bronze’s dramatic 2019 Liverpool v Man City is now the league’s biggest rivalry and the bitterness is growing Megan Rapinoe: Born & brilliant in the U.S.A. A Liverpool legend in the making: Behind Virgil van Dijk’s remarkable rise to world’s best player It was only a little over 12 months ago that an A-League record 61,880 people packed into ANZ Stadium for the 13th Sydney derby – but on Saturday night for the 17th edition, there was only 36,433 in the stands at the same venue.The dwindling interest in the A-League has been evident over the last few weeks with only one game out of the 10 matches in rounds eight and nine cracking a crowd of 10,000-plus.
outbackEach bowl week, before teams engage in fierce competition on the field, they sometimes participate in friendly competition off it. Such was the case with Tennessee and Northwestern tonight. The two teams are in Tampa for the Outback Bowl, and both squads made it out to Splitsville for some pool and bowling. Who are you rooting for in tonight’s bowling competition, @Vol_Football or @NUFBFamily?? pic.twitter.com/Vt0x6cDGAq— Outback Bowl (@outbackbowl) December 27, 2015The game is heating up! #FootballInParadise pic.twitter.com/9TVFg62XAW— Outback Bowl (@outbackbowl) December 28, 2015. @NUFBFamily is in full swing pic.twitter.com/99hVZNvJBr— Outback Bowl (@outbackbowl) December 27, 2015Looks like a good time is being had by all. We don’t think the players will be as friendly on the field as they were on the lanes though.
Press Trust of India ManchesterJuly 11, 2019UPDATED: July 11, 2019 12:55 IST Taylor played a crucial knock of 74 runs against India in the semi-final (Reuters)HIGHLIGHTSNew Zealand beat India to reach their 2nd successive World Cup final on Wednesday4 years ago New Zealand were beaten by Australia in the final of the World CupBut Ross Taylor believes his team are better eqipped to handle the pressure of the final this time aroundEmboldened by the stunning win over fancied India in the semifinal, New Zealand’s seasoned batsman Ross Taylor says the team is better prepared this time for the title clash of the World Cup.Four years ago, New Zealand were hammered by Australia by seven wickets in the final, overawed by the occasion.At Lord’s on Sunday, Taylor believes the Black Caps will know what to expect and be better prepared to cope with the challenges of an ICC World Cup final.”I’d be lying if I said we weren’t a bit overawed by the change of scenery. I think we know what to expect, the pressures that come with it, we’ve been there before,” Taylor was quoted as saying in the ICC website.”You just have to enjoy it, it’s the Home of Cricket, I can’t think of a better place to play a final.”Whether it’s England or Australia, we have to enjoy the moment, put our best foot forward and hope for the best.”Taylor played a crucial role in New Zealand reaching the final, top-scoring with 74 in an 18-run victory over India at Old Trafford in a semi-final played over two days.After battling to 239 for eight, Matt Henry and Trent Boult combined to reduce India to 24 for four, and despite a fightback from Ravindra Jadeja (77) and Mahendra Singh Dhoni (50), the target proved beyond India with Jimmy Neesham taking a stunning catch to remove Dinesh Karthik and Martin Guptill effectively sealing it with a sensational run-out of Dhoni.advertisementHe added: “I woke up at three in the morning so I didn’t know how I was going to go out and bat. It was such a strange one, it was a Test match feeling almost, being not out overnight and being a bit restless.”But we talked about 240 being what Kane (Williamson) and I thought was a very competitive total. I don’t think a lot of people believed us. It was a really slow wicket and if anything it got better to bat once it rained.”The big boys up front were fantastic getting those three wickets and from there it was nice to be ahead of the game. Jadeja and Dhoni nearly took it away from us. There was some brilliance out there, the catch of Neesham, the run-out of Guptill without even the keeper there. Those highlights in a few years’ time will be something the team will never forget.”Prior to the tournament, Taylor had spoken of trying to emulate Chris Gayle and appear in a fifth World Cup at the age of 39.However, he admitted after this one that the final at Lord’s may well be his final appearance on this stage.He said, “I’ve said that Chris Gayle is my inspiration, he’s 39 and still playing but it’s probably a bit too far-fetched for me to still be playing.”Never say never but probably more than likely (it will be my last World Cup game).”Apart from the All Blacks, most New Zealand sides are underdogs, no matter what sport they play. It’s something we have embraced. It doesn’t sit well when we’re the favourites, we try to talk it down as much as possible.Also Read | Is MS Dhoni changing nationalities? If he does, we will consider him for New Zealand team: Kane WilliamsonAlso Read | World Cup 2019: Rohit Sharma must be feeling terrible, says Sachin TendulkarFor sports news, updates, live scores and cricket fixtures, log on to indiatoday.in/sports. Like us on Facebook or follow us on Twitter for Sports news, scores and updates.Get real-time alerts and all the news on your phone with the all-new India Today app. Download from Post your comment Do You Like This Story? Awesome! Now share the story Too bad. Tell us what you didn’t like in the comments Posted byAjay Tiwari Tags :Follow World Cup 2019Follow India vs New ZealandFollow Ross Taylor World Cup 2019: New Zealand better prepared this time for the final, says Ross TaylorAfter beating India in the World Cup 2019 semi-final on Wednesday, New Zealand batsman Ross Taylor is confident that his side will put up a better show in the all-important final at Lord’s on July 14.advertisement Next
TORONTO – Several Canadian companies have kept silent on whether they’re attending a major Saudi Arabia investment conference after the event was overshadowed by the apparent murder of Saudi journalist Jamal Khashoggi.This week’s Future Investment Initiative in Riyadh has seen numerous high-profile cancellations after Turkey accused the Saudi regime of killing Khashoggi, who had written critically of it.SNC-Lavalin, which has extensive business ties with Saudi Arabia, refused to say whether it would attend this year.“We opted not to answer anyone on this particular conference,” said SNC-Lavalin spokesman Nicolas Ryan, referring to numerous inquiries from reporters.Chantal Sorel, the company’s executive vice-president and managing director of capital, was a speaker at last year’s conference.A spokesperson for Canaccord Genuity Group Inc., whose executive chairman David Kassie is also listed as a 2017 speaker, said they would look into whether the company was attending but then did not respond to further inquiries.Bombardier Inc., which has an office and transit projects in the country, said it never planned to attend the conference.Other companies that attended last year’s conference said they had no plans to attend this year, including the Canada Pension Plan Investment Board and Brookfield Asset Management Inc.The Canadian government is also skipping this year’s conference, according to sources. Last year, then-natural resources minister Jim Carr attended the inaugural edition of the summit.Canada’s relationship with Saudi Arabia became strained in August, when Riyadh suspended diplomatic ties with Canada and expelled the Canadian ambassador after Foreign Affairs Minister Chrystia Freeland criticized the regime on Twitter for its arrest of social activists.Saudi Arabia has faced intense global pressure as Turkey continues to release details of its investigation of what happened after Khashoggi entered the Saudi consulate in Istanbul on Oct. 2.Key international figures who have pulled out of the conference include top business executives, U.S. Treasury Secretary Steven Mnuchin, European cabinet ministers, International Monetary Fund head Christine Lagarde and World Bank President Jim Yong Kim.Companies in this story: (TSX:SNC, TSX:CF, TSX:BBD.B)
Paris- France’s data protection watchdog on Wednesday fined Google 150,000 euros ($205,000) — the maximum possible — for failing to comply with its privacy guidelines for personal data.The watchdog, the CNIL, also ordered the US Internet giant to publish a statement relating to its decision on its French homepage for at least 48 hours within the next eight days.
The DMC said that 17,912 people still remain in evacuation camps around the country. The death toll from the bad weather experienced in the country since last week had reached 36 this afternoon with 7 still missing.According to the Disaster Management Center (DMC) the death toll rose from 34 to 36 today with the recovery of the bodies of 2 people reported missing. Over 300,000 people had been affected by the heavy rain, landslides and strong winds since early last week. The DMC said that over 4000 houses were fully damaged and around 10,272 houses partially damaged from the bad weather.Several families in Mannar were also evacuated today owing to floods.
WASHINGTON – Treasury Secretary Jacob Lew called on Europe’s leaders to pursue pro-growth policies in the short term rather than trim their budget deficits, noting that the U.S. economy is “inextricably tied” to the health of its global partners.Lew’s comments were delivered in a speech at Johns Hopkins University School of Advanced International Studies previewing this week’s global finance meetings in Washington.Earlier this week, the International Monetary Fund lowered its outlook for the world economy this year, predicting that government spending cuts will slow U.S. growth and keep the euro currency alliance in recession.Lew also said he would keep pressing other countries to avoid pursuing policies aimed at gaining trade advantages. The comments underscored U.S. concerns about China and Japan devaluing their currency to make their products cheaper overseas. by Martin Crutsinger, The Associated Press Posted Apr 17, 2013 4:15 pm MDT AddThis Sharing ButtonsShare to TwitterTwitterShare to FacebookFacebookShare to RedditRedditShare to 電子郵件Email US Treasury Secretary Lew calls on Europe to pursue more growth-friendly economic policies
In this Jan. 8, 2015 photo, a flag advertising a new home for sale flaps in the breeze in Richmond, Va. The Commerce Department reports on U.S. sales of new homes in January on Wednesday, Feb. 25, 2015. (AP Photo/Steve Helber) AddThis Sharing ButtonsShare to TwitterTwitterShare to FacebookFacebookShare to RedditRedditShare to 電子郵件Email by Josh Boak, The Associated Press Posted Feb 25, 2015 8:29 am MDT WASHINGTON – Sales of new U.S. homes were basically flat in January, evidence that recent job gains and relatively low mortgage rates have yet to spur the real estate market.The Commerce Department said Wednesday that new home sales slipped 0.2 per cent last month to a seasonally adjusted annual rate of 481,000. This marks a slight decrease from sales of 482,000 homes in December, but represents a solid 5.3 per cent gain from a year ago when harsh winter weather caused home-buying to stall.Despite the increasingly favourable economy, home sales have been sluggish at the start of the year. Snow has buried parts of the Northeast and Midwest, cutting into open house visits. Too few homes are being listed for sale, and those that are on the market still seem to be out of reach for many prospective buyers despite the recent hiring surge and historically low interest rates.Sales of existing homes last month sank 4.9 per cent to a seasonally adjusted annual rate of 4.82 million. Contributing to that nine-month low was a tight inventory of homes on the market that sent prices higher. That may be pushing some home shoppers to wait for more choices at more inviting prices.But builders have yet to significantly increase construction.Many firms are focused on selling to wealthier buyers, instead of competing on volume by constructing more houses at more affordable levels. The median sales price rose 9.1 per cent since January 2014 to $294,300.Toll Brothers, which specializes in higher-end homes, reported Monday that its quarterly profits shot up 78 per cent as the average price of a home sold by the Pennsylvania builder climbed to $821,500 from $766,100.And instead of upgrading to new houses, some homeowners are renovating their current properties, said Nino Sitchinava, principal economist at Houzz, the online resource for remodeling and home design.In many instances, baby boomers are putting in new kitchens and bathrooms, in addition to adapting their houses in order to age in place, Sitchinava said.The winter weather caused sales of new homes to halve in the Northeast, while the West experienced a slight drop and the South and Midwest each reported gains, according to the Commerce Department report.Home values are appreciating at a slower rate since 2014, yet they continue to outpace wage gains.Average hourly wages grew 2.2 per cent over the past 12 months, which is roughly half of the increase in home values, according to the Standard & Poor’s/Case-Shiller 20-city home price index released Tuesday.Economists do see reasons why home sales should improve this spring.Mortgage rates remain near historic lows. The average 30-year fixed mortgage rate was 3.76 per cent last week, according to the mortgage giant Freddie Mac. That has ticked up in recent weeks, but is far below the 4.33 per cent average from a year ago.And employers have hired at an accelerated clip over the past year. In the past three months alone, the U.S. economy has added more than 1 million jobs, the fastest three-month pace in 17 years. More Americans earning paychecks should eventually push home sales higher. US new home sales decrease just 0.2 per cent in January; housing market off to slow start
Plans for superboats along a stretch of the Thames are set to turn the area into San Tropez, Chelsea residents have complained. They “epitomised swinging London”, according to former resident Suzanne Spiro, “with parties and people jumping from boat to boat.” Houseboats have moored at Chelsea Reach, next to one of the plushest streets in Chelsea, Cheyne Walk, since the 1930s. The same developers also own nearby Cadogan Pier, and advertising material… But there are now concerns that the quaint boats are set to be replaced with “superboats”, worth up to £6 million each, after the Reach was bought by property developers Andrew Moffat, 44, and his wife Charlotte, 45 with backing from investors.
GRA headquartersThe Guyana Revenue Authority (GRA) says that taxpayers and companies can now file their tax returns online with the long awaited introduction of its electronic services (eServices) platform.According to the GRA “after signing up to enable user access, monthly and yearly Pay As You Earn (PAYE), Individual Income Tax, Corporation Tax, Individual Company and Property taxes, and Value Added Tax (VAT) returns can be efiled via the website https://eservices.gra.gov.gy.”See their full statement below:The Guyana Revenue Authority (GRA) launched some of its long awaited electronic services (eServices) platform to enable individual taxpayers and companies to submit tax returns with the click of a button.The way was paved, following the amendment to Section 3 of the Income Tax Act Chapter 81:01 which gives jurisdiction to the Commissioner-General to “authorise the use of electronic technology” and also “require electronic, documents and electronic signatures.” After signing up to enable user access, monthly and yearly Pay As You Earn (PAYE), Individual Income Tax, Corporation Tax, Individual Company and Property taxes, and Value Added Tax (VAT) returns can be efiled via the website https://eservices.gra.gov.gy.The launch comes at an opportune time as employers who are required to submit Employers Returns/Form 2 (a list of their employees’ names, payments, allowances and tax deductions) before February 28 can do so online and simultaneously make use of a utility capable of converting the said content into accurately completed income tax returns for each employee in bulk “pdf” format. Employees can thereafter uplift the forms from their employers, include other sources of income, if any, affix their signature and thereafter submit to the GRA using the drop box system.Taxpayers in all categories, particularly individuals with multiple sources of income, those who have been approved for Mortgage Interest Relief (MIR) and others who file returns on their own volition, are encouraged to sign up to eServices in order to file with ease and convenience. Sensitisation sessions have commenced to ensure employers are fully au-fait with this revolutionary approach to tax compliance. The GRA will also be partnering with the E-Governance Unit to provide assistance to various taxpayers at Information Communication Technology (ICT) hubs across the country.Taxpayers are being reminded that Income Tax Returns must be true and correct and to ensure that their emolument (7b) slips are attached and a current email address is provided when submitting. The GRA is also encouraging taxpayers to make use of the online fillable forms that are available on its website.The filing of Income Tax is a requirement of Section 60 of the said Act which states that “Every person shall on or before the prescribed day in every year deliver to the Commissioner-General a true and correct return of the whole of his income from every source whatsoever for the year immediately preceding the year of assessment, and shall if absent from Guyana give the name and address of an agent residing therein.” Share this:Click to share on Twitter (Opens in new window)Click to share on Facebook (Opens in new window)RelatedE-filing of taxes to be mandatory for certain companies- GRADecember 4, 2018In “Business”Four Tax Sites launchedApril 3, 2019In “Business”GRA introduces Automated Drivers Licence CardMarch 11, 2014In “Local News”
Updated 7.55pmTHE NATIONAL BROADCASTER has apologised for any confusion that may have been caused by one of its news bulletins on the Israel-Gaza conflict.The report from 23 July, shows woman in Gaza, shouting in the street. The accompanying voiceover says: “This Palestinian said she is ready to strap on an explosive device and fight”.However a petition set up after the broadcast claimed this was a mistranslation of what the woman had said and that she was actually talking about children dying.The online petition called for an immediate apology from RTÉ and has already been signed by more than 1,400 people.In a response to TheJournal.ie on the issue, RTÉ said the report was not a misinterpretation of what the woman said.It said the pictures and information came from a news service and the material contained a lengthy sequence of footage of the woman shouting in the street.The woman begins by referring to children dying, but she then goes on to say that she is ready to wear an explosive jacket and join the fight. The voiceover on the report was not intended to be a direct translation. The reporter was paraphrasing the woman’s view – clearly stated in the information RTÉ received – that she was ready to resist the Israeli offensive.“There was no attempt on RTÉ’s part to misconstrue the woman’s message and we apologise for any confusion caused,” the broadcaster added.The segment in question can be seen at 1.25 in this video.Originally published 9.41amRead: RTE is looking for members of the public to join its board>
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Now Playing Up Next Now Playing Up Next Videos Articles Now Playing Up Next Twitter Facebook Now Playing Up Next The Bella Twins to appear on ABC’s “Celebrity Family Feud” airing August 18 Hulk Hogan Will Host WWE’s ‘Crown Jewel’ Event In Saudi Arabia Hulk Hogan Says He’s Headed To WWE’s Crown Jewel Event Jason Namako RELATED ARTICLESMORE FROM AUTHOR Pinterest Hulk Hogan To Return To WWE At Crown Jewel Now Playing Up Next Twitterverse Responds To Hulk Hogan Hosting WWE’s ‘Crown Jewel’ Hulk Hogan WhatsApp Hulk Hogan Is Back With WWE Google+ Dwayne “The Rock” Johnson talks about missing wrestling, his childhood, Hobbs and Shaw WWE Hall of Famer Hulk Hogan appeared Monday morning on ABC’s “Good Morning America” in an interview that was taped this past Thursday (8/27) to tell his side of the story of the leaked racial rant by Radar-Online and the National Enquirer that Hogan made as part of a sex tape with the ex-wife of Bubba the Love Sponge, Heather Clem, that is currently part of an ongoning $100 million lawsuit with Gawker.com.Hogan noted that this has hit him the hardest out of all the things he has been through. Hogan said when the sex tape was recorded that had that racial rant, he was at the lowest point of his life and was suicidal. He was mad at his daughter Brooke and her then-boyfriend and had no idea he was being taped. Hogan said he is not a racist, he is embarassed by what he said and that it was wrong. Hogan said people need to understand that you inherit things by where you grow up and “where I grew up in Tampa”, all his friends would greet each other, black and white, saying that word (the N word), it was thrown around like it was nothing. Hogan said that it is fair to say he inherited a racial bias over time, due to the environment he grew up in. All his friends, black and white, would say that word on a daily basis and would greet each other with that in the morning, it was part of the culture he grew up in. Hogan asked for forgiveness from his fans, saying he’s not the Hulk Hogan character you have seen for years, I’m Terry Bollea, I’m just a normal man.Hogan brought up WWE distancing themselves from him adding, “My entire career, it was like it never happened.” Hogan began breaking down in tears when talking about his daughter, Brooke, defending him when the racial rants were leaked. Hogan said that if anyone should have disowned him, it should have been her, she should have been the one to throw me out the trash, but instead she showed me more love than anybody. Hogan said his daughter was so supportive, even though she was the “direction of his attack.” Hogan said he was mad at her when he made the rant, not her then-boyfriend. Hogan said his daughter told him, “I don’t need to forgive you, because I’m not mad at you.”The interview closed with Hogan saying that just because a person makes a mistake, you don’t throw them away. If everybody at their lowest point was judged on one thing they said and all of a sudden, their entire career was wiped out because of something from 10, 20 years ago, it’d be a sad world, people get better everyday, they get better. Hogan said that he is working to raise awareness of the impact hateful language can have, but would still give his right arm to be involved in pro wrestling again. However, it remains to be seen if WWE will allow that according to Hogan.The interviewer mentioned Hogan’s ongoing lawsuit with Gawker, but made it like that Hogan was removed from the WWE Hall of Fame and WWE removed him completely from their history when in reality, Hogan is still in the WWE Hall of Fame and his matches are still included on the WWE Network. Finally, the interviewer brought up that Hogan will be appearing on “Nightline” on Monday night to again tell his side of the story, taped last Thursday.This ended the segment.You can view video of the segment with Hogan below.ABC Latest News | Latest News VideosRecommended videosPowered by AnyClipHulk Hogan Will Host WWE’s ‘Crown Jewel’ Event In Saudi ArabiaVideo Player is loading.Play VideoPauseUnmuteDuration 0:28/Current Time 0:09Loaded: 100.00%0:10Remaining Time -0:19 FullscreenUp NextThis is a modal window.Beginning of dialog window. Escape will cancel and close the window.TextColorWhiteBlackRedGreenBlueYellowMagentaCyanTransparencyOpaqueSemi-TransparentBackgroundColorBlackWhiteRedGreenBlueYellowMagentaCyanTransparencyOpaqueSemi-TransparentTransparentWindowColorBlackWhiteRedGreenBlueYellowMagentaCyanTransparencyTransparentSemi-TransparentOpaqueFont Size50%75%100%125%150%175%200%300%400%Text Edge StyleNoneRaisedDepressedUniformDropshadowFont FamilyProportional Sans-SerifMonospace Sans-SerifProportional SerifMonospace SerifCasualScriptSmall CapsReset restore all settings to the default valuesDoneClose Modal DialogEnd of dialog window.Replay the list Netflix announces season three of GLOW set to premiere Friday, August 9